F R A M E W O R K (the what)
Minimize inflammation
Eat to live, don’t live to eat
Maintain diverse and healthy gut flora
Eat close to nature, minimize ingredients
Fulfill macro and micronutrient needs aligned with your personal DRIs using food first, then supplements
Maintain an omega-6 (AA) to omega-3 (EPA) ratio of 5:1 or less
Keep IGF1 and mTOR in check
Eat the least amount of protein to maintain and grow muscle mass
Reduce carbs in order to maintain the lowest possible fasting insulin
Fill the remainder with fat (after determining the amounts of carbs and protein based on the two above metrics)
M Y R E C I P E (the how)
Daily supplements sourced from medical-grade, tested manufacturers
Multivitamin
Vitamin d3
Resveratrol
Omega-3 (fish oil)
Biotin
Electrolytes
Ketogenic or low-carb diet, 60-70% fat, 20-25% protein, 10-15% carbs
Prioritize monounsaturated over saturated fat (e.g. olive oil, almonds, avocado, macadamia nuts)
30-40g of fiber daily
1 serving of fermented food daily (e.g. kimchi, sauerkraut, kefir)
No dairy
Grass-fed, organic meat only
Fish 5-7 days a week, primarily those high in omegas 3 and 6
Organic as often as possible
Minimize packaged or processed foods, choose ones with few known ingredients
1-2 coffees in the morning
Caloric restriction: daily caloric intake < (basal metabolic rate + calories burned from exercise)
16/8 intermittent fasting/time-restricted feeding (eating between 10am-6pm or 11am-7pm)
Use an app to track food and monitor caloric intake, macronutrient ratios, and catch nutrient deficiencies. Adjust diet/supplements accordingly.
Regularly test biomarkers, e.g. omega-3 index, brain health (link), vitamin D, CMP, CBC, lipid panel
R E S E A R C H (the why)
Ketogenic diet extends longevity and healthspan in adult mice
Nature.com: Calorie restriction is the most reasonable anti-ageing intervention
Longer daily fasting times improve health and longevity in mice
Harvard: Moderate coffee drinking may lower the risk of premature death
Microbiome and Longevity: Gut Microbes Send Signals to Host Mitochondria
Gut microbiota changes in the extreme decades of human life: a focus on centenarians
Caloric restriction lowers levels of innate immunity and inflammation
Unregulated inflammation shortens human functional longevity
Up Next:
Longevity Building Block #3: Movement